If you going to buy the speakers then yes they might work, but the Alienware M14X by itself will not able to reproduce 5.1 surround sound.
Dell | Alienware Technical Support
Opening your case does not void your warranty! Check out Alienware Artificial Intelligence
I can't always reply to PM's, if you need extra assistance visit:
I have the M14xR1 with the SoundBlaster Xi Software installed that gives the option for 5.1 Surround Sound. I disabled all Realtek options in Control Panel | Realtek HD Audio Manager and selected the SoundBlaster Software for all Sound options. But now, two Realtek audio programs load and when opening Task Manager | Processes, I see that the two programs are each taking up to 13% of the CPU total 36%. I always have to 'End Process' for the two Realtek programs, and then all is well. Anyone have a clue? Im fresh out of them. Thanks