Glen has already provided the 2 must read documents before configuring VP. Moreover, he has already updated that it depends what you are looking for capacity or performance?! The configuration and responses will vary according to that choice. Moreover, I wouldn't recommend to stress Vault Drives much by utilizing it to its full capacity, if performance is your aim!
I strongly suggest to read EMC CLARiiON Best Practices for Performance and Availability lates release with other 2 docs before making any changes! I bet it will help you understand the concept in a deeper sense! (To me, it has!)