Beyond 2.2TB in size using GPT (GUID Partition Table).

Windows 7 8 or 10 64 bit  support direct attached disk drives greater than 2.2TB in size using GPT (GUID Partition Table).

Non booting drives can use 32 bit software.

Disk drives greater than 2.2TB in non-RAID configurations.

Software RAID 0 (striped) and RAID 1 (mirrored) 

Raid 5 and Raid 10 are not software supported.  

This is also a limit of INTEL RST 

Single drives require INTEL RST 10.1 or higher.