Hard disk failed to start some three months after automatic Windows 10 upgrade. Subsequent efforts to load Dell repair utility proved futile. Ran PSA that listed Hard disk error. Does HDD Error 2000-0146 mean certain death of hard disk and require replacement as clean fresh install of Windows 10 returned System Thread Exception Not Handled or Bad Pool Header error alternatively.
Unplug the system disconnect or remove the battery and hold the power button for 30 sec. Re-run the diagnostics - if you get the same error, replace the drive.