Chris, I noticed you never answered the original poster. I am disappointed because I want to know the fix. I have the same problem and have had it for almost a year, although I have had my system for almost 4 years -- Dell Inspiron with ST2010 Monitor. I have every energy-saving setting I can reach through Windows Control Panel set to Never and the monitor still goes into energy-saving mode, always while I am working at the computer (I never walk away now without turning off the monitor but leaving the CPU on), and nothing I can do wakes it up except powering off. I do not use the USB connection either.