SourceOne uses the service account profile on the server.
If the profiles are updated with the new name then it will be automatic.
If not, you would have to re-point all users along with the SourceOne servers to the new server.
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Sameer, In Exchange Clustered Environment, you need to provide cluster name when creating the profile. What happens when you provide Cluster name? does it resolve to the active host name of it stays as cluster name?
EMCSourceOne Profile should exist on Master Server, Worker Servers and Archives Servers(if archive server is going to index embedded msgs).