I know that there is a lot of issues since the release of Vista. I've been doing some research to learn more on Vista. Here are some links that may be of some help.
Vista Tweaking & Customization Guide- http://www.pro-networks.org/forum/about85935.html
Paul Thurrott's Vista Site- http://www.winsupersite.com/vista/
Tweakhound's Vista Site- http://www.tweakhound.com/vista/index.htm
Vista Installation Guide- http://www.pro-networks.org/forum/viewtopic.php?p=700609#700609
Some of these may or may not apply in all areas due to our PC's being an OEM Vista operating system. I would say that there is a lot of good information to learn here to improve your experience with Vista and how to make it work better for you.
Over the next year things should improve with fixes and driver updates.
Thanks for the other links. I'll add that to my bookmarks to research. There seems like many issues users struggle with. I wanted to start a thread with links users can review to help learn more about Vista and ways to make it work better.