Here is a link from Intel:
Intel Data Direct I/O Technology requires no industry enabling
Intel DDIO is enabled by default on all Intel Xeon processor E5 platforms. Intel DDIO has no hardware dependencies and is invisible to software, requiring no changes to drivers, operating systems, hypervisors, or applications. All I/O devices benefit from Intel DDIO, including Ethernet, InfiniBand*, Fibre Channel, and RAID.
The R320 will support it.