I have tried every possible solutions online, but none of it worked and I have tried new one. I hope this might help you.
I'm Using Dell Inspiron 5558, Windows 10 Home (x64) and i got this problem yesterday.
Before attempting this make sure you have updated all dell drivers and intel drivers successfully.
If you open Device Manager in Control Panel, and under Human Interface Devices -> I2C HID Device is showing "This device cannot start. (Code 10). A request for the HID descriptor failed.", and the touchpad clicks is working but not the gestures, then I got the correct solution that worked for me.
See if there is a file "hidi2c.inf" in "C:\Windows\System32\DriverStore\FileRepository\hidi2c.inf_amd64_xxxxxxxxxxxxxxxx" (where x is some random id). Right Click and Choose Install.
If it shows Operation completed, you can see that the gestures come working and options to modify in Windows Settings app.