If you install Windows 10 onto a Latitude xx80 laptop with a Skylake processor, the touchpad may become inoperable due to the touchpad now being based on the I2C protocol rather than the Legacy PS/2 protocol.
No cause information.
Once Windows 10 and most drivers are installed, there are no bangs in Device Manager but the touchpad is still inoperative if the Intel Serial IO driver was not loaded. Download and install the Intel Serial IO driver for your operating system, which provides the necessary virtual connection between the I2C bus and Windows.
Go to the Dell Drivers & Downloads and search for the Intel Serial IO driver under the Chipset category to download the latest driver version of the file.
No HID or mouse devices are listed in Device Manager:
The touchpad resides under the 9D61 I2C Host Controller (currently no devices are detected as shown in the image below):
HID and Mice devices are listed:
The touchpad is detected under the 9D61 I2C Host Controller: