Aurora-R4, video card upgrade

Hi guys, I have an Alienware R4 Aurora, purchased in 2014, with the following features:

- CPU: Intel(R) Core(TM) i7-4820K CPU @ 3.70GHz;

- RAM: 16 GB;

- HD1: Samsung SSD 850 EVO 500GB ;

- HD2: 1 TB SATA;

- Video Card: AMD Radeon(TM) R9 270 2 GB;

- Monitor: Dell Ultrasharp U2412M (1920x1200).

I want to replace the video card with one more modern and fast, can you indicate me some model (possibly AMD) that I can install without problems?.

Thanks in advance Antonio