You are not alone here. Same issue as yours in a Alienware 17 r5 and a lot of other users. Dell represetantive suggests this. Please try the following steps: Uninstall Alienware Command Center and ALL Add Ons from Programs and Features (OC Controls, AlienFX, Sound, etc.) following ALL the steps in this article: https://www.dell.com/support/article/us/en/04/sln303405/c%C3%B3mo-eliminar-y-volver-a-instalar-el-ce... Download and Install the latest Alienware Command Center from the MS Store (You will require a MS account). Open Command Center. You will get an error saying "No AlienFX Devices Detected". Disregard the massage for now. The Command Center will ask for deployment of several add ons. Download and install each of them (please consider that you will likely need to log to your MS Account several times for this process to complete successfully, do not skip ANY of the log in(s)). So, if no installation is skipped, your Command Center should be fully ready and all add ons will now appear on the bottom of the Home Page. At that moment, please restart the PC and ReOpen the Command Center. The error message should now be gone and you should be able to control the lights. If the error still appears, but you can still navigate to FX Tab and change colors, then please keep in mind that by the 3rd week of August, we will release a new version of Alienware Command Center that should address this issues.

Hi, 

If you are still experiencing this issue, send me a private message with your Service Tag so we can look further into this.