spyware

everything seems to be running slow ran adaware and spysweeper and cleaned up what i can...ran hijackthis and below is what it found...can someone tell what elese i need to do....
                                                                                                                                                                  R3 - Default URLSearchHook is missing
O2 - BHO: AcroIEHlprObj Class - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Adobe\Acrobat 6.0\Reader\ActiveX\AcroIEHelper.dll
O2 - BHO: ST - {9394EDE7-C8B5-483E-8773-474BF36AF6E4} - C:\Program Files\MSN Apps\ST\01.02.3000.1002\en-xu\stmain.dll
O2 - BHO: MSNToolBandBHO - {BDBD1DAD-C946-4A17-ADC1-64B5B4FF55D0} - C:\Program Files\MSN Apps\MSN Toolbar\01.02.3000.1001\en-us\msntb.dll
O3 - Toolbar: McAfee VirusScan - {BA52B914-B692-46c4-B683-905236F6F655} - c:\progra~1\mcafee.com\vso\mcvsshl.dll
O3 - Toolbar: MSN - {BDAD1DAD-C946-4A17-ADC1-64B5B4FF55D0} - C:\Program Files\MSN Apps\MSN Toolbar\01.02.3000.1001\en-us\msntb.dll
O3 - Toolbar: &Radio - {8E718888-423F-11D2-876E-00A0C9082467} - C:\WINDOWS\System32\msdxm.ocx
O4 - HKLM\..\Run: [VirusScan Online] "c:\PROGRA~1\mcafee.com\vso\mcvsshld.exe"
O4 - HKLM\..\Run: [MCAgentExe] c:\PROGRA~1\mcafee.com\agent\mcagent.exe
O4 - HKLM\..\Run: [MCUpdateExe] C:\PROGRA~1\mcafee.com\agent\mcupdate.exe
O4 - HKLM\..\Run: [NvCplDaemon] RUNDLL32.EXE C:\WINDOWS\System32\NvCpl.dll,NvStartup
O4 - HKLM\..\Run: [nwiz] nwiz.exe /install
O4 - HKLM\..\Run: [TraySantaCruz] C:\WINDOWS\system32\tbctray.exe
O4 - HKCU\..\RunOnce: [SantaCruzCpl] C:\Program Files\Turtle Beach\Santa Cruz\Control Panel\SantaCruzCpl.exe /restore
O9 - Extra button: (no name) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\j2re1.4.2_06\bin\npjpi142_06.dll
O9 - Extra 'Tools' menuitem: Sun Java Console - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\j2re1.4.2_06\bin\npjpi142_06.dll
O16 - DPF: {01111C00-3E00-11D2-8470-0060089874ED} (Support.com ActionRunner Class) - http://help.rr.com/Foundrysdccommon/download/tgctlar.cab
O16 - DPF: {1C955F3B-5B32-4393-A05D-24B4970CD2A1} - http://streamp.babenet.com/cabs/videox.cab
O16 - DPF: {38F5F92F-BD40-40DF-A569-6C1FCB638190} (InSPECS3_0 Control) - http://www.powerleap.com/cab_files/InSPECS3_0.cab
O16 - DPF: {56336BCB-3D8A-11D6-A00B-0050DA18DE71} (RdxIE Class) - http://software-dl.real.com/06c4a02ae9af4801bd17/netzip/RdxIE601.cab
O16 - DPF: {6414512B-B978-451D-A0D8-FCFDF33E833C} (WUWebControl Class) - http://v5.windowsupdate.microsoft.com/v5consumer/V5Controls/en/x86/client/wuweb_site.cab?1104714067625
O16 - DPF: {A90A5822-F108-45AD-8482-9BC8B12DD539} (Crucial cpcScan) - http://www.crucial.com/controls/cpcScanner.cab
O16 - DPF: {B38870E4-7ECB-40DA-8C6A-595F0A5519FF} (MsnMessengerSetupDownloadControl Class) - http://messenger.msn.com/download/MsnMessengerSetupDownloader.cab
O23 - Service: Diskeeper - Executive Software International, Inc. - C:\Program Files\Executive Software\Diskeeper\DkService.exe
O23 - Service: InstallDriver Table Manager - Macrovision Corporation - C:\Program Files\Common Files\InstallShield\Driver\1050\Intel 32\IDriverT.exe
O23 - Service: McAfee.com McShield - Unknown - c:\PROGRA~1\mcafee.com\vso\mcshield.exe
O23 - Service: McAfee SecurityCenter Update Manager - McAfee, Inc - C:\PROGRA~1\McAfee.com\Agent\mcupdmgr.exe
O23 - Service: McAfee.com VirusScan Online Realtime Engine - Networks Associates Technology, Inc - c:\PROGRA~1\mcafee.com\vso\mcvsrte.exe
O23 - Service: NVIDIA Display Driver Service - NVIDIA Corporation - C:\WINDOWS\System32\nvsvc32.exe

thanks