yes to both ..HBAnywhere will ask you to reboot as soon as you upgrade the firmware. PowerPath will insert new modules so most likely willl require reboot as well. Take a look at these documents:

Home > Support > Technical Documentation and Advisories > Software ~ P-R ~ Documentation > PowerPath Family > PowerPath Multipathing > Installation/Configuration

Home > Support > Technical Documentation and Advisories > Host Connectivity/HBAs

Make sure your future config is in the support matrix by running it through E-lab navigator

Home > Support > Interoperability and Product Lifecycle Information > E-Lab Interoperability Navigator

Thankyou