R720 Memory questions

Hello,

I just purchased an R720 Server for home lab and need some info..

I have never had server before so very new to this..

For Server DDR3 16GB ECC RDIMM quad rank memory I read the sample memory configs in the manual.. But I am still confused by it.

If I install 1 Quad Rank 16gb per channel can i then populate all the other slots for both cpus with 16gb 2Rx4 ram?

Or does the quak rank ram still force me to leave green slots empty?

I know if I did 2 quak rank per channel then Green would need to be empty.

But I did not see example for using just 1 quad rank per channel and then populating all the rest of the slots with 2Rx4.

Also are there any important updates for BIOS, Firmware, Drivers or other I need to install?

Thanks

Gren