The short answer is yes and the support for what OS's are supported can be found in the VPLEX SSM here: https://elabnavigator.emc.com/vault/pdf/EMC_VPLEX_ESSM.pdf

However, since your query is on ESX 6 and that hasn't made it into the SSM for this support yet, I would suggest you reach out to your EMC account team to file an RPQ or try to find out when it will be supported. ESX 5.x is supported.

HTH,

-K

Thank you sir!