To keep it short:

I have a VNXe3200 passing VMware Datastores through iSCSI to a Windows Server 2008 R2.

I am using that Datastore to create a new Disk Volume under Windows Server and then using that space as a file storage area.

My question is: Is there a drawback to using a Datastore as a Windows Server volume, instead of a normal LUN? Both appear to show up fine and be perfectly usable on my Windows Server, but I've read that datastores are primarily for virtual machines. I found this out a bit late and if there are no cons to doing it this way, it would save me some trouble.