PowerConnect 6224 iSCSI Enable

I am running a SAN off of a Power Connect 6224 and was going through the setups on the Power Connect. I noticed that the iSCSI was not enabled on the switch. Can I enable the iSCSI config while servers are accessing the SAN through the PC6224?

Just wondering if I need to shutdown all servers linked to the PC6224.

We only have one PC6224 switch right now, we will be purchasing another one soon for redundancy.