VSAN Question.

Question about the best practices for VSAN:
There is an application talking to Oracle DB. The Oracle DB server is connected to DMX and the application servers are connected to Clariion CX-3.
All of these hosts and Storage systems are connected via CiscoMDS.

We would like to separate this application traffic from others and would like to create a VSAN for the application hosts . This will result in application hosts and CX-3 in one VSAN and the DB Hosts and the DMX in another VSAN.

Is this a better approach ? Any concerns about keeping the DB and Applications on separate VSANs ? Any comments or suggestions welcome.

Thanks in advance