Virus, Spyware etc infested Dell 4550

Can anyone please help with this one?  I have tried everything.

Here is the Logfile of Trend Micro HijackThis v2.0.2
Scan saved at 20:31:45, on 13/11/2008
Platform: Windows XP SP2 (WinNT 5.01.2600)
MSIE: Internet Explorer v7.00 (7.00.6000.16735)
Boot mode: Normal

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\Program Files\Lavasoft\Ad-Aware\aawservice.exe
C:\WINDOWS\system32\spoolsv.exe
C:\WINDOWS\Explorer.EXE
C:\PROGRA~1\AVG\AVG8\avgwdsvc.exe
C:\WINDOWS\System32\drivers\CDAC11BA.EXE
C:\WINDOWS\System32\CTsvcCDA.exe
C:\WINDOWS\System32\inetsrv\inetinfo.exe
C:\Program Files\Java\jre1.6.0_02\bin\jusched.exe
C:\Program Files\Creative\SBLive\Diagnostics\diagent.exe
C:\Program Files\Common Files\Real\Update_OB\realsched.exe
C:\Program Files\QuickTime\qttask.exe
C:\Program Files\Internet Explorer\IEXPLORE.EXE
C:\PROGRA~1\AVG\AVG8\avgrsx.exe
C:\Program Files\NavNT\vptray.exe
C:\Program Files\Roxio\Media Experience\DMXLauncher.exe
C:\Program Files\Common Files\Roxio Shared\9.0\SharedCOM\RoxWatchTray9.exe
C:\Program Files\Roxio\Drag-to-Disc\DrgToDsc.exe
C:\PROGRA~1\AVG\AVG8\avgtray.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\ctfmon.exe
C:\WINDOWS\System32\MsPMSPSv.exe
C:\PROGRA~1\AVG\AVG8\avgemc.exe
C:\Program Files\Internet Explorer\IEXPLORE.EXE
C:\Program Files\Registry Mechanic\RegMech.exe
C:\Program Files\Spybot - Search & Destroy\TeaTimer.exe
C:\Program Files\Common Files\Roxio Shared\9.0\SharedCOM\RoxMediaDB9.exe
C:\Program Files\Common Files\Roxio Shared\9.0\SharedCOM\RoxWatch9.exe
C:\Program Files\Common Files\Roxio Shared\9.0\SharedCOM\CPSHelpRunner.exe
C:\WINDOWS\system32\wuauclt.exe
C:\Downloads\Hijackthis\HiJackThis.exe

R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = about:blank
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://go.microsoft.com/fwlink/?LinkId=69157
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://go.microsoft.com/fwlink/?LinkId=54896
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Bar = http://uk.red.clientapps.yahoo.com/customize/btyahoo/defaults/sb/*http://uk.docs.yahoo.com/info/bt_side.html
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://go.microsoft.com/fwlink/?LinkId=69157
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant = about:blank
O2 - BHO: AcroIEHlprObj Class - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Adobe\Acrobat 6.0\Reader\ActiveX\AcroIEHelper.dll
O2 - BHO: WormRadar.com IESiteBlocker.NavFilter - {3CA2F312-6F6E-4B53-A66E-4E65E497C8C0} - C:\Program Files\AVG\AVG8\avgssie.dll
O2 - BHO: Spybot-S&D IE Protection - {53707962-6F74-2D53-2644-206D7942484F} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O2 - BHO: {93bfe59d-5577-62b9-4c54-47a186899aa6} - {6aa99868-1a74-45c4-9b26-7755d95efb39} - C:\WINDOWS\system32\odmlsjag.dll (file missing)
O2 - BHO: SSVHelper Class - {761497BB-D6F0-462C-B6EB-D4DAF1D92D43} - C:\Program Files\Java\jre1.6.0_02\bin\ssv.dll
O2 - BHO: (no name) - {7E853D72-626A-48EC-A868-BA8D5E23E045} - (no file)
O2 - BHO: Windows Live Sign-in Helper - {9030D464-4C02-4ABF-8ECC-5164760863C6} - C:\Program Files\Common Files\Microsoft Shared\Windows Live\WindowsLiveLogin.dll
O2 - BHO: AVG Security Toolbar - {A057A204-BACC-4D26-9990-79A187E2698E} - C:\PROGRA~1\AVG\AVG8\AVGTOO~1.DLL
O2 - BHO: Windows Live Toolbar Helper - {BDBD1DAD-C946-4A17-ADC1-64B5B4FF55D0} - C:\Program Files\Windows Live Toolbar\msntb.dll
O3 - Toolbar: Windows Live Toolbar - {BDAD1DAD-C946-4A17-ADC1-64B5B4FF55D0} - C:\Program Files\Windows Live Toolbar\msntb.dll
O3 - Toolbar: AVG Security Toolbar - {A057A204-BACC-4D26-9990-79A187E2698E} - C:\PROGRA~1\AVG\AVG8\AVGTOO~1.DLL
O4 - HKLM\..\Run: [diagent] "C:\Program Files\Creative\SBLive\Diagnostics\diagent.exe" startup
O4 - HKLM\..\Run: [UpdReg] C:\WINDOWS\UpdReg.EXE
O4 - HKLM\..\Run: [SunJavaUpdateSched] "C:\Program Files\Java\jre1.6.0_02\bin\jusched.exe"
O4 - HKLM\..\Run: [websx] C:\Program Files\websx\int143514.exe -auto
O4 - HKLM\..\Run: [sysme] C:\WINDOWS\System32\sysme.exe
O4 - HKLM\..\Run: [Disc Detector] C:\Program Files\Creative\ShareDLL\CtNotify.exe
O4 - HKLM\..\Run: [IE Menu Extension toolbar] rundll32.exe "C:\PROGRA~1\IEMENU~1\tbextn.dll" DllShowTB
O4 - HKLM\..\Run: [Logitech Hardware Abstraction Layer] KHALMNPR.EXE
O4 - HKLM\..\Run: [TkBellExe] "C:\Program Files\Common Files\Real\Update_OB\realsched.exe"  -osboot
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\qttask.exe" -atboottime
O4 - HKLM\..\Run: [SpamBlocker] C:\Program Files\SpamBlockerUtility\Bin\4.8.4.0\SbOEAddOn.exe
O4 - HKLM\..\Run: [SBI] C:\Documents and Settings\Alfie\Local Settings\Temporary Internet Files\Content.IE5\1FQX11GO\install_sbd_en[1].exe
O4 - HKLM\..\Run: [SM_IAN] C:\Program Files\AdvancedCleaner Free\ian_monitor.exe
O4 - HKLM\..\Run: [BIND SUPPORT SEEK FIRST] C:\Documents and Settings\All Users\Application Data\dumb pure bind support\site bait.exe
O4 - HKLM\..\Run: [vptray] C:\Program Files\NavNT\vptray.exe
O4 - HKLM\..\Run: [DMXLauncher] "C:\Program Files\Roxio\Media Experience\DMXLauncher.exe"
O4 - HKLM\..\Run: [RoxWatchTray] "C:\Program Files\Common Files\Roxio Shared\9.0\SharedCOM\RoxWatchTray9.exe"
O4 - HKLM\..\Run: [RoxioDragToDisc] "C:\Program Files\Roxio\Drag-to-Disc\DrgToDsc.exe"
O4 - HKLM\..\Run: [AVG8_TRAY] C:\PROGRA~1\AVG\AVG8\avgtray.exe
O4 - HKCU\..\Run: [ctfmon.exe] C:\WINDOWS\system32\ctfmon.exe
O4 - HKCU\..\Run: [Yahoo! Pager] C:\Program Files\Yahoo!\Messenger\ypager.exe -quiet
O4 - HKCU\..\Run: [My Web Search Community Tools] "C:\Program Files\MyWebSearch\bar\2.bin\m3IMPipe.exe"
O4 - HKCU\..\Run: [Link4] C:\DOCUME~1\Alfie\APPLIC~1\OOZEMF~1\bind bait grid.exe
O4 - HKCU\..\Run: [RegistryMechanic] C:\Program Files\Registry Mechanic\RegMech.exe /H
O4 - HKCU\..\Run: [SpybotSD TeaTimer] C:\Program Files\Spybot - Search & Destroy\TeaTimer.exe
O4 - HKUS\S-1-5-18\..\Run: [ctfmon.exe] C:\WINDOWS\System32\CTFMON.EXE (User 'SYSTEM')
O4 - HKUS\.DEFAULT\..\Run: [ctfmon.exe] C:\WINDOWS\System32\CTFMON.EXE (User 'Default user')
O4 - Global Startup: Microsoft Office.lnk = C:\Program Files\Microsoft Office\Office10\OSA.EXE
O8 - Extra context menu item: &MSN Search - res://C:\Program Files\MSN Toolbar Suite\TB\02.05.0001.1119\en-us\msntb.dll/search.htm
O8 - Extra context menu item: &Search - ?p=ZNxuk100YYGB
O8 - Extra context menu item: &Windows Live Search - res://C:\Program Files\Windows Live Toolbar\msntb.dll/search.htm
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~2\Office10\EXCEL.EXE/3000
O8 - Extra context menu item: Open in new background tab - res://C:\Program Files\MSN Toolbar Suite\TAB\02.05.0001.1119\en-us\msntabres.dll/229?e91cf907bab244a1a3b7dffc9247b7cb
O8 - Extra context menu item: Open in new foreground tab - res://C:\Program Files\MSN Toolbar Suite\TAB\02.05.0001.1119\en-us\msntabres.dll/230?e91cf907bab244a1a3b7dffc9247b7cb
O9 - Extra button: (no name) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\WINDOWS\system32\msjava.dll
O9 - Extra 'Tools' menuitem: Sun Java Console - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\WINDOWS\system32\msjava.dll
O9 - Extra button: (no name) - {DFB852A3-47F8-48C4-A200-58CAB36FD2A2} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O9 - Extra 'Tools' menuitem: Spybot - Search & Destroy Configuration - {DFB852A3-47F8-48C4-A200-58CAB36FD2A2} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O9 - Extra button: (no name) - {e2e2dd38-d088-4134-82b7-f2ba38496583} - C:\WINDOWS\Network Diagnostic\xpnetdiag.exe
O9 - Extra 'Tools' menuitem: @xpsp3res.dll,-20001 - {e2e2dd38-d088-4134-82b7-f2ba38496583} - C:\WINDOWS\Network Diagnostic\xpnetdiag.exe
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O18 - Protocol: linkscanner - {F274614C-63F8-47D5-A4D1-FBDDE494F8D1} - C:\Program Files\AVG\AVG8\avgpp.dll
O20 - AppInit_DLLs: avgrsstx.dll
O20 - Winlogon Notify: hggffdd - hggffdd.dll (file missing)
O23 - Service: Lavasoft Ad-Aware Service (aawservice) - Lavasoft - C:\Program Files\Lavasoft\Ad-Aware\aawservice.exe
O23 - Service: AVG Free8 E-mail Scanner (avg8emc) - AVG Technologies CZ, s.r.o. - C:\PROGRA~1\AVG\AVG8\avgemc.exe
O23 - Service: AVG Free8 WatchDog (avg8wd) - AVG Technologies CZ, s.r.o. - C:\PROGRA~1\AVG\AVG8\avgwdsvc.exe
O23 - Service: C-DillaCdaC11BA - Macrovision - C:\WINDOWS\System32\drivers\CDAC11BA.EXE
O23 - Service: Creative Service for CDROM Access - Creative Technology Ltd - C:\WINDOWS\System32\CTsvcCDA.exe
O23 - Service: DefWatch - Symantec Corporation - C:\Program Files\NavNT\defwatch.exe
O23 - Service: InstallDriver Table Manager (IDriverT) - Macrovision Corporation - C:\Program Files\Roxio\Roxio Easy Media Creator 9 Suite\InstallShield\Driver\1050\Intel 32\IDriverT.exe
O23 - Service: Norton AntiVirus Client (Norton AntiVirus Server) - Symantec Corporation - C:\Program Files\NavNT\rtvscan.exe
O23 - Service: Roxio UPnP Renderer 9 - Sonic Solutions - C:\Program Files\Roxio\Roxio Easy Media Creator 9 Suite\Digital Home 9\RoxioUPnPRenderer9.exe
O23 - Service: Roxio Upnp Server 9 - Sonic Solutions - C:\Program Files\Roxio\Roxio Easy Media Creator 9 Suite\Digital Home 9\RoxioUpnpService9.exe
O23 - Service: LiveShare P2P Server 9 (RoxLiveShare9) - Sonic Solutions - C:\Program Files\Common Files\Roxio Shared\9.0\SharedCOM\RoxLiveShare9.exe
O23 - Service: RoxMediaDB9 - Sonic Solutions - C:\Program Files\Common Files\Roxio Shared\9.0\SharedCOM\RoxMediaDB9.exe
O23 - Service: Roxio Hard Drive Watcher 9 (RoxWatch9) - Sonic Solutions - C:\Program Files\Common Files\Roxio Shared\9.0\SharedCOM\RoxWatch9.exe

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End of file - 10070 bytes
Thanks,

mccartneym