Here is just a list of issues I've encountered so far:

1. SA (SupportAssist) will cause video and audio stutters randomly.
(Uninstalling SA fixed this issue)

2. A split-second static noise when the system goes from no sound to sound. This doesn't always occur but it is annoying when it does. I am using the latest sound driver downloaded from the Dell website.

3. Performance power option missing from Windows and AWCC (Alienware Command Center). You can see it from this JustIN Tech Tips Youtube

4. Strange video tearing when streaming and video playback on certain things.
(Power management mode set to "Prefer maximum performance under NVIDIA Control Panel fixes this issue)

I contacted another user on Reddit with the same Aurora R15 configuration and funny enough he is also having the same issue.