Send a pic of the crash code so I can identify what it means as the AGA is just a eGPU holder for a graphics card so anything that x16 PCIe should work and anything within the range of the PSUs power limit.

Doesn’t it do it automatically since it turns off the built in video card in the laptop?

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I installed the new drivers from NVidia  and same result occurs. Installed the drivers with clean installation option. Also, ran test with BIOS 1.3.0, 1.4.0 and 1.5.0 (released 8/21/2020). Same option occurs every time.

Excellent question. Tried that this morning and same result ... BSOD.

I was thinking it also turns offs (or stops using it automatically). I disabled the internal video card to at least run test. Same results of system crashing.

What error code you getting.

Stop code: VIDEO_TDR_FAILURE

What failed: nvlddmkm.sys

https://docs.microsoft.com/en-us/windows-hardware/drivers/debugger/bug-check-0x116---video-tdr-failure

Sorry to hear you are experiencing the same issue. Please keep us updated. I have until 9/10/2020 to return my unit. If Alienware can't resolve this issue, I'm going to return it instead of taking the risk.

Have you guys tried manually disabling the internal GPU from the task manager and then use the graphics amp?

I have the exact same issue. M17 R3 connected to a graphics amplifier with a founders edition 2080 ti and all I get are blue screen crashes once I install the latest Nvidia drivers. I'm on the phone with Alienware tech support right now but it seems like they're getting no where.  

Yes. I disabled the internal video card, but same result = BSOD

This clearly wasn't tested by Dell engineers. I see that a new BIOS was released that states the following:

Version 1.5.0

- Improved the user experience for Alienware Graphics Amplifier.

I installed it and it made no difference. Still getting blue screen crashes. 

Try booting into safe mode and connect it.