We're using a mix of Latitude 5580, 5590, and 7490 laptops.  We have Windows 10 and Office 365 ProPlus installed with MFA enabled for Office 365.  Sometimes Outlook will say that it needs password.  When you click that notification a white box will flash on the screen and then disappear.  Nothing seems to help except for one of two things:  Either setting EnableADAL to 0 in the registry and using Legacy authentication with an App Password (which isn't an acceptable workaround for us), or shutting down the computer, unplugging the power, plugging in the power, and turning on.  It seems like this is resetting something in the hardware, and I suspect it's TPM related.  Has anyone else seen similar issues with these Latitudes?  We've also had problems where computers will randomly ask for BitLocker recovery keys at bootup, and ignoring that and doing the reboot process will allow the system to boot normally again. We've used Dell Command | Update to ensure the latest drivers and firmware are installed, but the issues still happen sometimes.  We don't have these issues with any of the Lenovos we have and those have the same versions of OS/software installed.

Thoughts?