@mcmalburg  No, there is no way to do that, and Dell's relocation of the Home/End keys from their previous location on the left/right arrow keys up to the top row -- and on existing F keys -- has generated a lot of complaints.  The fact that Fn+Up/Down still activates PgUp/Dn means people have to move their hands to completely different areas of the keyboard to use closely related navigation keys.  Lenovo did the same thing, but they at least created dedicated Home/End keys on the top row rather than making them "Fn mapped" onto F keys -- AND they retained the ability to activate Home/End by pressing Fn+Left/Right as well.  The somewhat good news is that on at least some newer Dell systems, BIOS updates have restored the ability to use Fn+Left/Right to activate Home/End, but I don't know if that's true of the XPS 15 9510.  But update your BIOS before you try it just in case that was added with an update.  Otherwise, your only real option would be to use an application like AutoHotKey to create some other keyboard shortcut to activate Home/End, but those shortcuts would not be able to use the Fn key, since the OS doesn't see the Fn key "independently".  Only the system firmware does, and then all the OS sees is a command that results from pressing Fn and something else, e.g. it wouldn't see "Fn+Up", but rather just "PgUp".

@mcmalburg  To be clear since I didn't directly address your hoped-for setup in my above reply, there's no way to simultaneously have the F keys be single press AND have Home/End also be single press, UNLESS you used something like Autohotkey to remap some existing single press keys to Home/End -- but then you'd be giving up whatever those repurposed keys were supposed to do, unless you remapped THOSE functions to some multi-key combination.  But if your system allows Fn+Left/Right to be used for Home/End, you might find that this works fairly well for you especially given that it facilitates efficient use of PgUp/Dn, both of which require the Fn key and involve keys in the same area.