I need some help in getting rid of excessive pop ups, malware, etc.

 

I just had a new hard drive put in my computer. The old one went after just 4 months. After the new hard drive was installed, I installed Windows. Then before I went on the internet I made sure that the Windows Firewall was on and that my Norton AntiVirus was up to date. After that I started getting all these pop ups. It didn't matter what webpage I was on. I downloaded Spybot and Adaware and ran those. They found numerous problems. I deleted what these programs found. But, I am still getting these pop ups. Spybot found Malware on my system. I keep running these two programs. I even downloaded Spyblaster. This morning when I came to this forum I got another popup. Could it have come from the new drive that was put in my computer? It wasn't a brand new drive, it was a "refurbished" one. When I installed Windows I didn't do a full reformat. I just ran the Quick format. Should I reinstall Windows again and reformat the hard drive? If this would help I would try it. I'm getting tired of all this junk on my system. Thanks for any help.