Area-51 R5, compatible with RTX 3000 series GPU's?

If you have 1500W power supply I see no issues.

The 850W power supply may have issues because power spikes may cause the system to reboot and crash.

Other than that if you have current bios I see no issues.

Also keep in mind that Crossfire and SLI have been abandoned by ATI and NVIDIA. as of Jan 2021.

https://www.youtube.com/watch?v=i1dGQiNfCAc

Re: Is anyone actually running them with this setup? 

user benchmark says yes 

i Have an Area 51 R5, and i am looking to upgrade too. Can anyone confirm if this is compatible, also how can i check the PSU power i have ??

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@INXSEX wrote:

i Have an Area 51 R5, and i am looking to upgrade too. Can anyone confirm if this is compatible, also how can i check the PSU power i have ??

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You can look it up by checking your PC as shipped here:  https://www.dell.com/support/home/en-us/product-support/product/alienware-area51-r4/overview

I have an Area 51 R5 and just upgraded my 1080Ti to a MSI AMD Radeon 6900XT Gaming X Trio and have no issues.  My understanding is that if you ordered or bought you R5 with a single GPU you have an 850W Power supply.  I chose the MSI brand due to it only requires or uses 300W of power VS other brands may pull more.  The only issue I had was when I installed the 6900XT and booted up I got a blue screen and had to re-install Windows.  I think was due to not uninstalling the Nvidia drivers and software prior to installing the new GPU.  I did read that this can happen when changing from Nvidia to AMD.  I use my R5 strictly for gaming and some light web browsing and had all my games installed on a 2nd drive, so I did not lose anything.  

Hope this Helps. 

Update.  I upgraded my 1080ti with a MSI AMD Radeon 6900XT Gaming Z Trio but I had issues when upgrading to windows 11.  It disabled the TPM under the BIOS (greyed out) and was not able to turn it back on or change the settings.  I installed my 1080ti back and all the BIOS functions were available again.  I found it a bit strange due to the MSI 6900XT supports UEFI according to the specs on the MSI website but while the 6900XT was installed I was not able to change the UEFI settings and there is no CSM option under the BIOS for the R5 so I had no way to troubleshoot.  I ended contacting Dell support and they were not able to figure out why the 6900XT was causing issues with the BIOS. I do have the latest BIOS update for my R5.  Just food for thought just in case you want to upgrade to Windows II as you have to enable TPM under the BIOS to be able to upgrade. 

Hope this helps.