PowerEdge - Unity Direct to Host ISCSI connectivity

Hello =)

Greetings of the day!

Query:

Servers: Power Edge R750xs *3

Storage: Unity XT 380F DPE

OS: ESXI 8.0

Ports: 10GBaseT AF (ZR)

Is direct to host ISCSI supported? It is supported for Windows/Mac with the proper multi-path software. I can't seem to find the proper documentation for ESXI, along with the cabling guide.

Fairly new to IT. Help and guidance is most appreciated.