Help with trojan, webpage hijacking, spyware

Have a PC that, after running Spysweeper, still is getting webpage hijacked. Suspect a trojan, etc. Below is an output from hijackthis. Any ideas? Thanks.

Logfile of HijackThis v1.98.2
Scan saved at 6:48:44 PM, on 8/16/2004
Platform: Windows XP SP1 (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 SP1 (6.00.2800.1106)

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\csrss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\spoolsv.exe
C:\WINDOWS\Explorer.EXE
C:\Program Files\AIM95\aim.exe
C:\WINDOWS\System32\winupd.exe
C:\Program Files\MSN Messenger\MsnMsgr.Exe
C:\Program Files\Webroot\Spy Sweeper\SpySweeper.exe
C:\WINDOWS\System32\wuauclt.exe
C:\PROGRA~1\MICROS~2\Office\OUTLOOK.EXE
C:\WINDOWS\System32\rasdlg.exe
C:\highjacker\HijackThis.exe

R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://us7.hpwis.com/
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://srch-us7.hpwis.com/
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.yahoo.com
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://www.epix.net
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.yahoo.com
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,CustomizeSearch =
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Window Title = Microsoft Internet Explorer provided by epix(TM) Internet Services
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyServer = http=localhost:1042
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyOverride = ;127.0.0.1;localhost;
R0 - HKCU\Software\Microsoft\Internet Explorer\Toolbar,LinksFolderName =
R3 - URLSearchHook: (no name) - {87766247-311C-43B4-8499-3D5FEC94A183} - (no file)
F2 - REG:system.ini: UserInit=C:\WINDOWS\System32\Userinit.exe
O2 - BHO: AcroIEHlprObj Class - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Adobe\Acrobat 6.0\Reader\ActiveX\AcroIEHelper.dll
O2 - BHO: G1.GZ - {79C03BC5-6C55-4B5B-921F-C02B6F1ABD7B} - C:\DOCUME~1\ALLUSE~1\APPLIC~1\Pribi\Pribi.dll
O2 - BHO: Viewpoint Toolbar BHO - {A7327C09-B521-4EDB-8509-7D2660C9EC98} - C:\Program Files\Viewpoint\Viewpoint Toolbar\ViewBarBHO.dll
O3 - Toolbar: &Radio - {8E718888-423F-11D2-876E-00A0C9082467} - C:\WINDOWS\System32\msdxm.ocx
O3 - Toolbar: hp toolkit - {B2847E28-5D7D-4DEB-8B67-05D28BCF79F5} - C:\HP\EXPLOREBAR\HPTOOLKT.DLL
O3 - Toolbar: (no name) - {2CDE1A7D-A478-4291-BF31-E1B4C16F92EB} - (no file)
O3 - Toolbar: (no name) - {ACB1E670-3217-45C4-A021-6B829A8A27CB} - (no file)
O3 - Toolbar: Viewpoint Toolbar - {F8AD5AA5-D966-4667-9DAF-2561D68B2012} - C:\Program Files\Viewpoint\Viewpoint Toolbar\ViewBar.dll
O4 - HKLM\..\Run: [win_upd2.exe] C:\WINDOWS\System32\WINdirect.exe
O4 - HKCU\..\Run: [AIM] C:\Program Files\AIM95\aim.exe -cnetwait.odl
O4 - HKCU\..\Run: [rasdlg] C:\WINDOWS\System32\rasdlg.exe
O4 - HKCU\..\Run: [winupd.exe] C:\WINDOWS\System32\winupd.exe
O4 - HKCU\..\Run: [\IEService.exe] C:\DOCUME~1\ALLUSE~1\APPLIC~1\IESERV~1\IEService.exe
O4 - HKCU\..\Run: [key] C:\WINDOWS\System32\winxp.exe
O4 - HKCU\..\Run: [win_upd.exe] C:\WINDOWS\System32\WINdirect.exe
O4 - HKCU\..\Run: [win_upd2.exe] C:\WINDOWS\System32\WINdirect.exe
O4 - HKCU\..\Run: [\Pribi.exe] C:\DOCUME~1\ALLUSE~1\APPLIC~1\Pribi\Pribi.exe
O4 - HKCU\..\Run: [MsnMsgr] "C:\Program Files\MSN Messenger\MsnMsgr.Exe" /background
O4 - HKCU\..\Run: [SpySweeper] "C:\Program Files\Webroot\Spy Sweeper\SpySweeper.exe" /0
O4 - Startup: AdSubtract.lnk = C:\Program Files\interMute\AdSubtract\AdSub.exe
O4 - Startup: SpySubtract.lnk = C:\Program Files\interMute\SpySubtract\spysub.exe
O8 - Extra context menu item: &Viewpoint Search - res://C:\Program Files\Viewpoint\Viewpoint Toolbar\ViewBar.dll/CXTSEARCH.HTML
O8 - Extra context menu item: MyPoints - file://C:\Program Files\WebRebates\System\Temp\mypoints_script0.htm
O9 - Extra button: MktBrowser - {17A27031-71FC-11d4-815C-005004D0F1FA} - C:\Program Files\MarketBrowser\lmt\MarketBrowser_Launch.xpy (file missing)
O9 - Extra 'Tools' menuitem: MarketBrowser - {17A27031-71FC-11d4-815C-005004D0F1FA} - C:\Program Files\MarketBrowser\lmt\MarketBrowser_Launch.xpy (file missing)
O9 - Extra button: AIM - {AC9E2541-2814-11d5-BC6D-00B0D0A1DE45} - C:\Program Files\AIM95\aim.exe
O9 - Extra button: (no name) - {CD67F990-D8E9-11d2-98FE-00C0F0318AFE} - (no file)
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\MSMSGS.EXE
O9 - Extra 'Tools' menuitem: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\MSMSGS.EXE
O9 - Extra button: Point Alert - {16BF42FD-CA0A-4f48-819D-B0343254DD67} - file://C:\Program Files\WebRebates\System\Temp\mypoints_script0.htm (file missing) (HKCU)
O14 - IERESET.INF: START_PAGE_URL=http://www.epix.net
O15 - Trusted Zone: http://*.cdc.gov
O16 - DPF: {072D3F2E-5FB6-11D3-B461-00C04FA35A21} (CFForm Runtime) - http://www.dorneypark.com/CFIDE/classes/CFJava.cab
O16 - DPF: {30528230-99F7-4BB4-88D8-FA1D4F56A2AB} (YInstStarter Class) - http://us.dl1.yimg.com/download.yahoo.com/dl/installs/yinst20040510.cab
O16 - DPF: {44260C54-2BC1-4E3B-B312-3F0277544C8D} (Siebel Option Pack for IE 7.0.5) - https://wtiwebopt.axaonline.com/fins/14308/applets/SiebelOptionPack.cab
O16 - DPF: {9600F64D-755F-11D4-A47F-0001023E6D5A} (Shutterfly Picture Upload Plugin) - http://web1.shutterfly.com/downloads/Uploader.cab
O16 - DPF: {DBFF771D-3F92-4C70-9978-508738536F38} (CSConn Class) - https://wtiwebopt.axaonline.com/fins/14308/applets/csagent.cab
O16 - DPF: {E13F1132-4CA0-4005-84D3-51406E27D269} (BTDownloadCtrl Control) - http://www.shockwave.com/content/thinktanks/BTDownloadCtrl.cab
O16 - DPF: {E855A2D4-987E-4F3B-A51C-64D10A7E2479} (EPSImageControl Class) - http://tools.ebayimg.com/eps/activex/EPSControl_v1-32.cab
O16 - DPF: {E93A6FCA-C052-45DF-AC9B-B729066092F8} (Util Class) - https://isupport4.hp.com/motivedocs/linklauncher/MotUtil.cab
O16 - DPF: {FA13A9FA-CA9B-11D2-9780-00104B242EA3} (WildTangent Control) - http://install.wildtangent.com/bgn/partners/shockwave/blasterball2Remix/install.cab