SORRY misstyped !!!

Just press FN + F6 to lock or unlock the Windows key !

Out of curiosity, for the people where Fn+F6 disables the Windows key, what is the icon on that key to indicate that functionality?  On my Latitude 7480, the Fn graphic on the F6 key is Scroll Lock.

@WAR12  if your system doesn't have a Fn key dedicated to disabling the Windows key (I didn't even realize that was a thing), then you could use a tool like Autohotkey to cause Windows to ignore it.  Autohotkey is a hugely powerful application that can do all kinds of things, but if you just want it to block your Windows key sometimes, create a script with this as its only line:

#::return

In the line above, "#" is how Autohotkey refers to the Windows key.  The double colon ends the "trigger" key combination (you can have Autohotkey react to various key combinations and sequences, not just individual keys), and "return" ends the action statement.  A more typical Autohotkey scenario would be something like, "When this key combination is pressed, send this key sequence/output or perform this action", so you'd have those commands between the trigger key combination and return, but having no action is still a valid script, and the result is that when the script is active in Autohotkey, nothing at all will happen when you press the Start key.

From there you can set the script to be loaded at startup if you want to Windows key to be disabled most of the time, or you can just keep it in a readily accessible location and enable/disable it as needed.