Flash (having surpassed Java as the most-exploited browser plug-in) has been hit yet again:  the Angler Exploit Kit will install Bedep, a distribution botnet that can load multiple payloads on the infected host.

According to MalwareBytes, users with the latest version of Internet Explorer and latest version of Flash, can successfully protect themselves by using [free] AntiExploit program https://www.malwarebytes.org/antiexploit/

For details, including which O/S and browsers have been confirmed vulnerable, see  http://malware.dontneedcoffee.com/2015/01/unpatched-vulnerability-0day-in-flash.html 

http://threatpost.com/exploit-for-flash-zero-day-appears-in-angler-exploit-kit/110569

https://blog.malwarebytes.org/exploits-2/2015/01/new-adobe-flash-zero-day-found-in-the-wild/