What operating system? Do you have two drives, a DVD-ROM and a CD-RW?

I have Windows 2000 Professional, and yes I have two drives.  I have tried both of them. 

Sounds like an autoplay issue. Disable autoplay, then try inserting and running discs of various types (music, video, data, etc.) manually. If that's good, then you need to fix autoplay.

Here are the instructions for disabling autoplay (sorry, a bit complicated in 2000):

Windows 2000/XP

Run the Registry Editor (REGEDIT.EXE).

Navigate to HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Services\Cdrom.

Double-click the Autorun value, and type 0 for its value. (If it's not there, create it by selecting Edit -> New -> DWORD Value, and typing "Autorun" for its name.)

You may have to log out and then log back in for this change to take effect.

 

Note: With this solution, Windows will no longer be notified when you insert a new CD. To make sure the correct icon and title for the current CD are displayed in My Computer and Explorer, press F5 to refresh the window.

Thank you very much!!!! It's working once more.