i2b2 - The Learning Health System
I2B2 Collective data empowers health care treatments
i2b2 tranSMART: The Learning Health System
In 2020, Dell partnered with the i2b2 tranSMART Foundation, a global nonprofit focused on enabling the promise of precision medicine to assist in creating virtual models of patients — known as digital medical twins. These twins are highly personalized to the patient and provide insights that facilitate precise recruitment into clinical trials. We started by focusing on COVID long-haul patients and are planning to expand to many more diseases, like cancer and neurological disease, as the program continues to expand and innovate. As of FY24, the digital medical twin effort encompasses more than 2.1 million patients worldwide.
PROJECT HIGHLIGHTS AI-enabled learning healthcare platform
The Learning Platform is an AI enabled healthcare platform that uses Dell Technologies’ modern infrastructure to create pools of de-identified patient data to produce digital twins across the globe. Researchers can then perform millions of individualized treatment simulations on the digital twins to determine the best possible therapy option for patients, based on genetic background and medical history.
HOW IT WORKS Leveraging the power of collective data and AI-driven research for individual impact
A Data Enclave—powered by an integration of Dell Technologies that includes PowerEdge, PowerStore, PowerScale and VMware Workspace ONE—is both the heart and brain of the digital twin operations. Researchers gather, store, and analyze de-identified data sourced from various monitoring systems and electronic health records and update the digital twins with real-time clinical data such as that collected through ventilators and cardiac monitors.
Identifying and accelerating treatment options around the globe
The Digital Twin effort encompasses 2.1 million patients worldwide, with the potential to expand to millions more. Patients from underrepresented populations are expected to make up a part of this growth, bringing more equity to the critical area of healthcare.
Researchers
- Access to de-identified patient data
- Collaboration with researchers
- Faster translation of research to application
Providers
- Treatment simulations for individual patients
- Precision medicine derived from over 800,000 patients
- Access to cutting-edge research results
Patients
- Potential for relevant, tailored treatments
- Access to targeted clinical trials
- Contribute to better health and quality of life
“By synthesizing this data into holistic models, we should be able to ensure greater accuracy in treatment and increase the success rates of clinical trials.”
DIANE KEOGH, EXECUTIVE DIRECTOR, I2B2 TRANSMART FOUNDATION
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